Fly seamlessly from Portland, Oregon to Knoxville and Maryville, Tennessee with Globitude Travels. Whether you are heading east to explore the Great Smoky Mountains or visiting downtown Knoxville, we offer competitive fares on trusted carriers. Book your trip from Portland International Airport (PDX) to McGhee Tyson Airport (TYS) today and enjoy incredible travel value.
Traveling from Portland (PDX) to Knoxville/Maryville (TYS) connects the Pacific Northwest with East Tennessee. McGhee Tyson Airport provides convenient access to both Knoxville's historic Market Square and the scenic gateway of Maryville. Visitors can explore a rich local food scene featuring authentic Southern barbecue and farm-to-table dining.
When planning your trip, consider Knoxville's four-season climate, featuring warm summers and mild winters ideal for outdoor activities. Top carriers serving this route include Delta Air Lines, Southwest Airlines, and American Airlines, offering smooth single-stop connections through major domestic hubs.
You can fly this route with Delta Air Lines, Southwest, and American Airlines, with Economy fares starting as low as $244.
Flights depart from Portland International Airport (PDX) in Oregon and arrive at McGhee Tyson Airport (TYS), which serves both Knoxville and Maryville, Tennessee.
Most flights on this route require a short layer or connection at a major hub such as Atlanta, Dallas, or Denver.
Booking during the shoulder seasons of late winter or early fall generally offers the cheapest airfares for this route.
Yes, you can call Globitude Travels directly to speak with an agent, compare airline deals, and complete your booking.
Globitude Travels is an independent travel agency — call 1-856-513-6369 or use the search above to compare live fares on this route. See our terms, privacy policy, refund policy and service fees for full details, or contact us any time.
Page updated September 13, 2026 · fare data refreshed automatically from live flight searches.
