Planning a trip from Columbia, South Carolina to vibrant San Antonio, Texas? Globitude Travels makes booking your journey simple and affordable. Whether you are traveling for business or eager to explore iconic spots like the historic Alamo and the River Walk, secure Delta Air Lines Economy seats starting from $308. Start planning your getaway today!
Flying from Columbia Metropolitan Airport (CAE) to San Antonio International Airport (SAT) links the charm of South Carolina with the rich culture of South Texas. Connecting flights through major hubs allow you to travel comfortably between these two dynamic cities.
Once you land in San Antonio, you will enjoy a warm climate and a legendary culinary scene famous for authentic Tex-Mex cuisine. Take time to explore distinct neighborhoods like the historic King William District, the bustling Pearl area, and the scenic walkways along the San Antonio River.
Flights depart from Columbia Metropolitan Airport (CAE) in South Carolina and land at San Antonio International Airport (SAT) in Texas.
Delta Air Lines provides Economy options on this route, with fares starting from $308 when booking through Globitude Travels.
Flights on this route typically include one layover at a major connecting hub prior to reaching San Antonio.
Travelers often find the lowest airfares during the shoulder seasons of September through November and late winter.
Yes, Globitude Travels offers phone booking assistance so travel agents can help you secure preferred fares and routing.
Globitude Travels is an independent travel agency — call 1-856-513-6369 or use the search above to compare live fares on this route. See our terms, privacy policy, refund policy and service fees for full details, or contact us any time.
Page updated September 13, 2026 · fare data refreshed automatically from live flight searches.